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MOTS-C (10mg)

MOTS-C (10mg)

$135.00 USD
$135.00 USD
Sale Sold out

MOTS-c (mitochondrial open-reading-frame of the 12S rRNA-c) peptide is a novel mitochondria-derived peptide. It is a short peptide composed of 16 amino acids, expressed in tissues and plasma, indicating a cell-specific and hormonal role.(1) With the potential to work both as a cell-specific compound and as a hormone, this peptide possibly acts by stimulating the AMP-activated protein kinase (AMPK) pathway. Only two mitochondrial-derived peptides (MDPs) have been studied, Humanin and MOTS-c. When metabolic stress occurs in the organism, the peptide is believed to translocate to the cellular nuclei and alter the gene expression. MOTS-c peptide may also be released extracellularly and is known as "mitochondrial hormone" or simply as "mitokine.” (2)(3)may stimulate further release of Oxytocin, leading to higher frequency and intensity of the contractions via a positive feedback mechanism.(3) The peptide appears to contribute to the contractions of myoepithelial cells found in the alveolar ducts of mammary glands. These contractions may stimulate milk ejection from alveolar ducts into the larger sinuses, thereby expelling milk. The positive feedback mechanism may also work here, with initial milk expulsion potentially stimulating increased Oxytocin circulation and continuous milk release.(3)

Warning: Sterile glass vial

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